Science Target Conference Systems, Ajman 4th International Environment Conference 2016

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CHEMODIVERSITY OF SOME ALGERIAN MEDICINAL PLANTS
hamada haba

Last modified: 2015-09-11

Abstract


Plants belonging to some genera as Euphorbia, Helianthemum, Astragalus and Erinacea growing in Algeria have been chemically studied by using chromatographic methods such as CC, TLC and HPLC. Structures of all the isolated bioactive compounds were determined mainly by 1-D (1H, 13C and DEPT) and 2-D NMR (COSY, HSQC, TOCSY, HMBC, NOESY, ROESY), UV, IR, mass spectrometry HR-ESI-MS, optical rotation and comparison with literature data. The isolated compounds belong to many classes of secondary metabolites as triterpenoids, lignans, saponins, flavonoids and isoflavonoids. Moreover, we have evaluated the antioxidant activity of the crude extract (EtOAc) and some isolated products of the species Erinacea anthyllis by two different methods: DPPH radical scavenging and ferric reducing power. The EtOAc and n-butanol extracts of the species Euphorbia bupluroides and Astragalus depressus were tested against three bacterial strains Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus, by the diffusion method on agar medium. The obtained results indicate that these species could be used as a source of antibacterial and anti-oxidant activities. Furthermore, this finding illustrates the interesting chemodiversity of selected species.